The Ebola Virus Interferon Antagonist VP24 Directly Binds STAT1 and Has a Novel, Pyramidal Fold

Ebolaviruses cause hemorrhagic fever with up to 90% lethality and in fatal cases, are characterized by early suppression of the host innate immune system. One of the proteins likely responsible for this effect is VP24. VP24 is known to antagonize interferon signaling by binding host karyopherin α pr...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhang, Adrianna P. P., Bornholdt, Zachary A., Liu, Tong, Abelson, Dafna M., Lee, David E., Li, Sheng, Woods, Virgil L., Saphire, Erica Ollmann
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285596/
https://ncbi.nlm.nih.gov/pubmed/22383882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002550
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