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Dysregulation of Wnt/β-catenin Signaling in Gastrointestinal Cancers
Aberrant Wnt/β-catenin signaling is widely implicated in numerous malignancies, including cancers of the gastrointestinal (GI) tract. Dysregulation of signaling is traditionally attributed to mutations in Axin, APC (adenomatous polyposis coli), and β-catenin that lead to constitutive hyperactivation...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3285553/ https://ncbi.nlm.nih.gov/pubmed/22155636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.12.001 |
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