Catechol-o-methyl transferase (COMT) val(158)met polymorphism and adolescent cortical development in patients with childhood-onset schizophrenia, their non-psychotic siblings, and healthy controls

Non-psychotic individuals at increased risk for schizophrenia show alterations in fronto-striatal dopamine signaling and cortical gray matter maturation reminiscent of those seen in schizophrenia. It remains unclear however if variations in dopamine signaling influence rates of structural cortical m...

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Main Authors:	Raznahan, Armin, Greenstein, Deanna, Lee, Yohan, Long, Robert, Clasen, Liv, Gochman, Pete, Addington, Anjene, Giedd, Jay N., Rapoport, Judith L., Gogtay, Nitin
Format:	Artigo
Sprog:	Inglês
Udgivet:	2011
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3285479/ https://ncbi.nlm.nih.gov/pubmed/21620981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2011.05.032
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Catechol-o-methyl transferase (COMT) val(158)met polymorphism and adolescent cortical development in patients with childhood-onset schizophrenia, their non-psychotic siblings, and healthy controls

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