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A sterol binding protein integrates endosomal lipid metabolism with TOR signaling and nitrogen sensing

Kes1, and other oxysterol binding protein (OSBP) superfamily members, are involved in membrane and lipid trafficking through trans-Golgi network (TGN) and endosomal systems. We demonstrate that Kes1 represents a sterol-regulated antagonist of TGN/endosomal phosphatidylinositol-4-phosphate signaling....

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Detalhes bibliográficos
Main Authors: Mousley, Carl J., Yuan, Peihua, Gaur, Naseem A., Trettin, Kyle D., Nile, Aaron H., Deminoff, Stephen J., Dewar, Brian J., Wolpert, Max, Macdonald, Jeffrey M., Herman, Paul K., Hinnebusch, Alan G., Bankaitis, Vytas A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285437/
https://ncbi.nlm.nih.gov/pubmed/22341443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.12.026
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