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HB-EGF is necessary and sufficient for Müller glia dedifferentiation and retina regeneration

Müller glia (MG) dedifferentiation into a cycling population of multipotent progenitors is crucial to zebrafish retina regeneration. The mechanisms underlying MG dedifferentiation are unknown. Here we report that heparin-binding epidermal-like growth factor (HB-EGF) is rapidly induced in MG residing...

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Bibliografske podrobnosti
Main Authors: Wan, Jin, Ramachandran, Rajesh, Goldman, Daniel
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285435/
https://ncbi.nlm.nih.gov/pubmed/22340497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.11.020
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