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HB-EGF is necessary and sufficient for Müller glia dedifferentiation and retina regeneration
Müller glia (MG) dedifferentiation into a cycling population of multipotent progenitors is crucial to zebrafish retina regeneration. The mechanisms underlying MG dedifferentiation are unknown. Here we report that heparin-binding epidermal-like growth factor (HB-EGF) is rapidly induced in MG residing...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3285435/ https://ncbi.nlm.nih.gov/pubmed/22340497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.11.020 |
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