Synthesis and physicochemical properties of oligonucleotides built with either alpha-L or beta-L nucleotides units and covalently linked to an acridine derivative.

Modified deoxynucleosides 2'-deoxy-beta-L-uridine, beta-L-thymidine, alpha-L-thymidine, 2'-deoxy-beta-L-adenosine and 2'-deoxy-alpha-L-adenosine were synthesized and assembled as homooligomers, respectively: octa-beta-L-deoxyuridylates, octa beta-L and alpha-L-thymidylates and tetra b...

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Main Authors: Asseline, U, Hau, J F, Czernecki, S, Le Diguarher, T, Perlat, M C, Valery, J M, Thuong, N T
Formato: Artigo
Idioma:Inglês
Publicado: 1991
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC328542/
https://ncbi.nlm.nih.gov/pubmed/1651474
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