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Translational studies of lipoprotein-associated phospholipase A2 in inflammation and atherosclerosis

OBJECTIVES: To examine the role of lipoprotein-associated phospholipase A2 (Lp-PLA(2)/PLA2G7) in human inflammation and coronary atherosclerosis. BACKGROUND: Lp-PLA(2) has emerged as a potential therapeutic target in coronary heart disease (CHD). Data supporting Lp-PLA(2) are indirect and confounded...

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Detalhes bibliográficos
Main Authors: Ferguson, Jane F, Hinkle, Christine C, Mehta, Nehal N, Bagheri, Roshanak, DerOhannessian, Stephanie L, Shah, Rhia, Mucksavage, Megan I, Bradfield, Jonathan P, Hakonarson, Hakon, Wang, Xuexia, Master, Stephen R, Rader, Daniel J, Li, Mingyao, Reilly, Muredach P
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285416/
https://ncbi.nlm.nih.gov/pubmed/22340269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2011.11.019
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