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The Cytoplasmic Domain of the HIV-1 Glycoprotein gp41 Induces NF-κB Activation Through TGF-β-Activated Kinase 1
The human and simian immunodeficiency viruses (HIV and SIV) primarily infect lymphocytes, which must be activated for efficient viral replication. We show that the cytoplasmic domain of the transmembrane glycoprotein gp41 (gp41CD) of both HIV-1 and SIV induces activation of NF-κB, a cellular factor...
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| Main Authors: | , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2012
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3285415/ https://ncbi.nlm.nih.gov/pubmed/22341466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2011.12.005 |
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