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Modified Low Density Lipoprotein Stimulates Complement C3 Expression and Secretion via Liver X Receptor and Toll-like Receptor 4 Activation in Human Macrophages

Complement C3 is a pivotal component of three cascades of complement activation. C3 is expressed in human atherosclerotic lesions and is involved in atherogenesis. However, the mechanism of C3 accumulation in atherosclerotic lesions is not well elucidated. We show that acetylated low density lipopro...

詳細記述

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書誌詳細
主要な著者: Mogilenko, Denis A., Kudriavtsev, Igor V., Trulioff, Andrey S., Shavva, Vladimir S., Dizhe, Ella B., Missyul, Boris V., Zhakhov, Alexander V., Ischenko, Alexander M., Perevozchikov, Andrej P., Orlov, Sergey V.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285363/
https://ncbi.nlm.nih.gov/pubmed/22194611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.289322
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