Loss of Soluble N-Ethylmaleimide-sensitive Factor Attachment Protein α (αSNAP) Induces Epithelial Cell Apoptosis via Down-regulation of Bcl-2 Expression and Disruption of the Golgi

Intracellular trafficking represents a key mechanism that regulates cell fate by participating in either prodeath or prosurvival signaling. Soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein α (αSNAP) is a well known component of vesicle trafficking machinery that mediates intermembr...

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Main Authors: Naydenov, Nayden G., Harris, Gianni, Brown, Bryan, Schaefer, Katherine L., Das, Swadesh K., Fisher, Paul B., Ivanov, Andrei I.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Cell Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285361/
https://ncbi.nlm.nih.gov/pubmed/22194596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.278358
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