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Death-associated Protein 6 (Daxx) Mediates cAMP-dependent Stimulation of Cyp11a1 (P450scc) Transcription

SF-1 is a key transcription factor for all steroidogenic genes. It up-regulates the expression of the steroidogenic Cyp11a1 gene in the adrenal in a pathway stimulated by cAMP through HIPK3-mediated JNK/c-Jun phosphorylation. In the present study, we have investigated the factors mediating cAMP-depe...

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Autors principals: Lan, Hsin-Chieh, Wu, Chih-Feng, Shih, Hsiu-Ming, Chung, Bon-chu
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285359/
https://ncbi.nlm.nih.gov/pubmed/22199361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.307603
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