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Dimerization and Cytoplasmic Localization Regulate Hippo Kinase Signaling Activity in Organ Size Control
The Hippo (Hpo) signaling pathway controls organ size by regulating the balance between cell proliferation and apoptosis. Although the Hpo function is conserved, little is known about the mechanism of how its kinase activity is regulated. Based on structural information, we performed mutation-functi...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3285349/ https://ncbi.nlm.nih.gov/pubmed/22215676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.310334 |
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