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RNA Chaperone Activity of Human La Protein Is Mediated by Variant RNA Recognition Motif
La proteins are conserved factors in eukaryotes that bind and protect the 3′ trailers of pre-tRNAs from exonuclease digestion via sequence-specific recognition of UUU-3′OH. La has also been hypothesized to assist pre-tRNAs in attaining their native fold through RNA chaperone activity. In addition to...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3285324/ https://ncbi.nlm.nih.gov/pubmed/22203678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.276071 |
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