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Optimization of the CHARMM additive force field for DNA: Improved treatment of the BI/BII conformational equilibrium

The B-form of DNA can populate two different backbone conformations: BI and BII, defined by the difference between the torsion angles ε and ζ (BI = ε-ζ < 0 and BII = ε-ζ > 0). BI is the most populated state, but the population of the BII state, which is sequence dependent, is significant and a...

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Detalhes bibliográficos
Main Authors: Hart, Katarina, Foloppe, Nicolas, Baker, Christopher M., Denning, Elizabeth J., Nilsson, Lennart, MacKerell, Alexander D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285246/
https://ncbi.nlm.nih.gov/pubmed/22368531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ct200723y
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