Histamine Derived from Probiotic Lactobacillus reuteri Suppresses TNF via Modulation of PKA and ERK Signaling

Beneficial microbes and probiotic species, such as Lactobacillus reuteri, produce biologically active compounds that can modulate host mucosal immunity. Previously, immunomodulatory factors secreted by L. reuteri ATCC PTA 6475 were unknown. A combined metabolomics and bacterial genetics strategy was...

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Hlavní autoři: Thomas, Carissa M., Hong, Teresa, van Pijkeren, Jan Peter, Hemarajata, Peera, Trinh, Dan V., Hu, Weidong, Britton, Robert A., Kalkum, Markus, Versalovic, James
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285189/
https://ncbi.nlm.nih.gov/pubmed/22384111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031951
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