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Thioredoxin Glutathione Reductase as a Novel Drug Target: Evidence from Schistosoma japonicum

BACKGROUND: Schistosomiasis remains a major public health concern affecting billions of people around the world. Currently, praziquantel is the only drug of choice for treatment of human schistosomiasis. The emergence of drug resistance to praziquantel in schistosomes makes the development of novel...

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Autori principali: Song, LiJun, Li, JiaHuang, Xie, ShuYing, Qian, ChunYan, Wang, Jie, Zhang, Wei, Yin, XuRen, Hua, ZiChun, Yu, ChuanXin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285170/
https://ncbi.nlm.nih.gov/pubmed/22384025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031456
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