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Phosphodiesterase 4 inhibition attenuates plasma volume loss and transvascular exchange in volume-expanded mice

NON-TECHNICAL SUMMARY: When vascular volume is expanded, atrial natriuretic peptide (ANP) released from the heart acts to restore plasma volume by increasing renal water excretion, causing vasodilatation and increasing vascular permeability to water and macromolecules. Previous experiments using mic...

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Detalhes bibliográficos
Main Authors: Lin, Yueh-Chen, Adamson, Roger H, Clark, Joyce F, Reed, Rolf K, Curry, Fitz-Roy E
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285067/
https://ncbi.nlm.nih.gov/pubmed/22083598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.213447
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