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Genetic depletion indicates a late role for U5 snRNP during in vitro spliceosome assembly.

The pre-mRNA splicing pathway is highly conserved from yeast (S. cerevisiae) to mammals. Of the four snRNPs involved in splicing three (U1, U2 and U4/U6) have been shown to be essential for in vitro splicing. To examine the remaining snRNP, we utilized our previously described genetic procedures (Se...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Séraphin, B, Abovich, N, Rosbash, M
Format: Artigo
Language:Inglês
Published: Oxford University Press 1991
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC328474/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1830649/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.14.3857
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