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Deficient Plakophilin-1 Expression Due to a Mutation in PKP1 Causes Ectodermal Dysplasia-Skin Fragility Syndrome in Chesapeake Bay Retriever Dogs

In humans, congenital and hereditary skin diseases associated with epidermal cell-cell separation (acantholysis) are very rare, and spontaneous animal models of these diseases are exceptional. Our objectives are to report a novel congenital acantholytic dermatosis that developed in Chesapeake Bay re...

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Detalhes bibliográficos
Main Authors: Olivry, Thierry, Linder, Keith E., Wang, Ping, Bizikova, Petra, Bernstein, Joseph A., Dunston, Stanley M., Paps, Judy S., Casal, Margret L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3284538/
https://ncbi.nlm.nih.gov/pubmed/22384142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032072
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