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Differential Occurrence of Streptococcus pneumoniae Serotype 11E Between Asymptomatic Carriage and Invasive Pneumococcal Disease Isolates Reflects a Unique Model of Pathogen Microevolution

Background. Streptococcus pneumoniae is a commensal colonizer of the human nasopharynx (NP) that causes disease after evasion of host defenses and dissemination. Pneumococcal strains expressing the newly identified serotype 11E arise from antigenically similar 11A progenitors by genetic inactivation...

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Bibliographic Details
Main Authors: Calix, Juan J., Dagan, Ron, Pelton, Stephen I., Porat, Nurith, Nahm, Moon H.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3284216/
https://ncbi.nlm.nih.gov/pubmed/22267713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/cir953
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