Hypoxia upregulates PGI-synthase and increases PGI(2) release in human vascular cells exposed to inflammatory stimuli

Hypoxia affects vascular function and cell metabolism, survival, growth, and motility; these processes are partially regulated by prostanoids. We analyzed the effect of hypoxia and inflammation on key enzymes involved in prostanoid biosynthesis in human vascular cells. In human vascular smooth muscl...

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Detalhes bibliográficos
Main Authors: Camacho, Mercedes, Rodríguez, Cristina, Guadall, Anna, Alcolea, Sonia, Orriols, Mar, Escudero, José-Román, Martínez-González, José, Vila, Luis
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3284164/
https://ncbi.nlm.nih.gov/pubmed/21296955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M011007
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