Urokinase Plasminogen Receptor and the Fibrinolytic Complex Play a Role in Nerve Repair after Nerve Crush in Mice, and in Human Neuropathies

Remodeling of extracellular matrix (ECM) is a critical step in peripheral nerve regeneration. In fact, in human neuropathies, endoneurial ECM enriched in fibrin and vitronectin associates with poor regeneration and worse clinical prognosis. Accordingly in animal models, modification of the fibrinoly...

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Main Authors: Rivellini, Cristina, Dina, Giorgia, Porrello, Emanuela, Cerri, Federica, Scarlato, Marina, Domi, Teuta, Ungaro, Daniela, Carro, Ubaldo Del, Bolino, Alessandra, Quattrini, Angelo, Comi, Giancarlo, Previtali, Stefano C.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283718/
https://ncbi.nlm.nih.gov/pubmed/22363796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032059
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