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The Bacterial Preparation OK432 Induces IL-12p70 Secretion in Human Dendritic Cells in a TLR3 Dependent Manner

Dendritic cells (DC) used in therapeutic cancer immunotherapy have to be able to stimulate T cells resulting in an immune response that can efficiently target the cancer cells. One of the critical hurdles has been the lack of IL-12p70 production when maturating the DC, which is rectified by using th...

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Detalhes bibliográficos
Main Authors: Hovden, Arnt-Ove, Karlsen, Marie, Jonsson, Roland, Appel, Silke
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283639/
https://ncbi.nlm.nih.gov/pubmed/22363584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031217
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