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Stimulus-Specific Activation and Actin Dependency of Distinct, Spatially Separated ERK1/2 Fractions in A7r5 Smooth Muscle Cells

A proliferative response of smooth muscle cells to activation of extracellular signal regulated kinases 1 and 2 (ERK1/2) has been linked to cardiovascular disease. In fully differentiated smooth muscle, however, ERK1/2 activation can also regulate contraction. Here, we use A7r5 smooth muscle cells,...

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Detalhes bibliográficos
Main Authors: Vetterkind, Susanne, Saphirstein, Robert J., Morgan, Kathleen G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283592/
https://ncbi.nlm.nih.gov/pubmed/22363435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030409
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