A Three-Gene Model to Robustly Identify Breast Cancer Molecular Subtypes

BACKGROUND: Single sample predictors (SSPs) and Subtype classification models (SCMs) are gene expression–based classifiers used to identify the four primary molecular subtypes of breast cancer (basal-like, HER2-enriched, luminal A, and luminal B). SSPs use hierarchical clustering, followed by neares...

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Main Authors: Haibe-Kains, Benjamin, Desmedt, Christine, Loi, Sherene, Culhane, Aedin C., Bontempi, Gianluca, Quackenbush, John, Sotiriou, Christos
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2012
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283537/
https://ncbi.nlm.nih.gov/pubmed/22262870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djr545
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