Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients

BACKGROUND: The diagnostic and pathophysiological relevance of antibodies to aquaporin-4 (AQP4-Ab) in patients with neuromyelitis optica spectrum disorders (NMOSD) has been intensively studied. However, little is known so far about the clinical impact of AQP4-Ab seropositivity. OBJECTIVE: To analyse...

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Main Authors: Jarius, Sven, Ruprecht, Klemens, Wildemann, Brigitte, Kuempfel, Tania, Ringelstein, Marius, Geis, Christian, Kleiter, Ingo, Kleinschnitz, Christoph, Berthele, Achim, Brettschneider, Johannes, Hellwig, Kerstin, Hemmer, Bernhard, Linker, Ralf A, Lauda, Florian, Mayer, Christoph A, Tumani, Hayrettin, Melms, Arthur, Trebst, Corinna, Stangel, Martin, Marziniak, Martin, Hoffmann, Frank, Schippling, Sven, Faiss, Jürgen H, Neuhaus, Oliver, Ettrich, Barbara, Zentner, Christian, Guthke, Kersten, Hofstadt-van Oy, Ulrich, Reuss, Reinhard, Pellkofer, Hannah, Ziemann, Ulf, Kern, Peter, Wandinger, Klaus P, Bergh, Florian Then, Boettcher, Tobias, Langel, Stefan, Liebetrau, Martin, Rommer, Paulus S, Niehaus, Sabine, Münch, Christoph, Winkelmann, Alexander, Zettl U, Uwe K, Metz, Imke, Veauthier, Christian, Sieb, Jörn P, Wilke, Christian, Hartung, Hans P, Aktas, Orhan, Paul, Friedemann
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283476/
https://ncbi.nlm.nih.gov/pubmed/22260418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-14
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