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How the DNA damage response determines the fate of HTLV-1 Tax-expressing cells

How the Human T lymphotropic virus type 1 (HTLV-1) Tax protein stimulates proliferation while triggering cell cycle arrest and senescence remains puzzling. There is also a debate about the ability of Tax to activate or inhibit the DNA damage response. Here, we comment on these different activities a...

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Détails bibliographiques
Auteurs principaux: Boxus, Mathieu, Willems, Luc
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283471/
https://ncbi.nlm.nih.gov/pubmed/22221708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-9-2
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