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Opposing Effects of Age and Calorie Restriction on Molecular Determinants of Myocardial Ischemic Tolerance

We test the hypothesis that moderate calorie restriction (CR) reverses negative influences of age on molecular determinants of myocardial stress resistance. Postischemic contractile dysfunction, cellular damage, and expression of regulators of autophagy/apoptosis and of prosurvival and prodeath kina...

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Autori principali: Peart, Jason N., See Hoe, Louise, Pepe, Salvatore, Johnson, Peter, Headrick, John P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283441/
https://ncbi.nlm.nih.gov/pubmed/22236144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/rej.2011.1226
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