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Early steps in steroidogenesis: intracellular cholesterol trafficking: Thematic Review Series: Genetics of Human Lipid Diseases

Steroid hormones are made from cholesterol, primarily derived from lipoproteins that enter cells via receptor-mediated endocytosis. In endo-lysosomes, cholesterol is released from cholesterol esters by lysosomal acid lipase (LAL; disordered in Wolman disease) and exported via Niemann-Pick type C (NP...

詳細記述

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書誌詳細
主要な著者: Miller, Walter L., Bose, Himangshu S.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Biochemistry and Molecular Biology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283258/
https://ncbi.nlm.nih.gov/pubmed/21976778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R016675
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