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Platelet-Derived Growth Factor B Chain Is a Novel Target Gene of Cocaine-Mediated Notch1 Signaling: Implications for HIV-Associated Neurological Disorders

Neuroinflammation associated with HIV-1 infection is exacerbated in cocaine-abusing, HIV+ individuals. The underlying mechanisms are, in part, attributable to disruption of the blood–brain barrier modulated by cocaine via platelet-derived growth factor B chain (PDGF-B). Since Notch signaling plays a...

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Detalhes bibliográficos
Main Authors: Yao, Honghong, Duan, Ming, Hu, Guoku, Buch, Shilpa
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283138/
https://ncbi.nlm.nih.gov/pubmed/21880906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2330-11.2011
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