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Protein Disulfide Isomerase Chaperone ERP-57 Decreases Plasma Membrane Expression of the Human GnRH Receptor

Retention of misfolded proteins by the endoplasmic reticulum (ER) is a quality control mechanism involving the participation of endogenous chaperones such as calnexin (CANX) which interact and restrict plasma membrane expression of gonadotropin releasing hormone receptor (GnRHR), a G protein coupled...

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Bibliographic Details
Main Authors: Yánez, Rodrigo Ayala, Conn, P. Michael
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282983/
https://ncbi.nlm.nih.gov/pubmed/20029959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbf.1622
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