Effects of 2-chloroadenine substitution in DNA on restriction endonuclease cleavage reactions.

The purine analog, 2-chloro-2'-deoxyadenosine triphosphate (CldATP), was incorporated enzymatically in place of dATP into the minus strand of M13mp18 duplex DNA. Its effect on protein-DNA interactions was assessed by determining the amount of DNA cleavage by type II restriction endonucleases. S...

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Bibliographic Details
Main Authors: Hentosh, P, McCastlain, J C
Format: Artigo
Language:Inglês
Published: 1991
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC328283/
https://ncbi.nlm.nih.gov/pubmed/1647525
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