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Thiazolidinedione Treatment Decreases Oxidative Stress in Spontaneously Hypertensive Heart Failure Rats Through Attenuation of Inducible Nitric Oxide Synthase–Mediated Lipid Radical Formation

The current study was designed to test the hypothesis that inducible nitric oxide synthase (iNOS)-mediated lipid free radical overproduction exists in an insulin-resistant rat model and that reducing the accumulation of toxic metabolites is associated with improved insulin signaling and metabolic re...

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Detalhes bibliográficos
Main Authors: Kadiiska, Maria B., Bonini, Marcelo G., Ruggiero, Christine, Cleland, Ellen, Wicks, Shawna, Stadler, Krisztian
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282814/
https://ncbi.nlm.nih.gov/pubmed/22315311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1091
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