Severe Pandemic H1N1 2009 Infection Is Associated with Transient NK and T Deficiency and Aberrant CD8 Responses

BACKGROUND: It is unclear why the severity of influenza varies in healthy adults or why the burden of severe influenza shifts to young adults when pandemic strains emerge. One possibility is that cross-protective T cell responses wane in this age group in the absence of recent infection. We therefor...

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Hlavní autoři: Fox, Annette, Hoa, Le Nguyen Minh, Horby, Peter, van Doorn, H. Rogier, Trung, Nguyen Vu, Ha, Nguyen Hong, Cap, Nguyen Trung, Phu, Vu Dinh, Ha, Nguyen Minh, Ngoc, Diep Nguyen Thi, Ngoc, Bich Vu Thi, Kieu, Huong Tran Thi, Taylor, Walter R., Farrar, Jeremy, Wertheim, Heiman, Kinh, Nguyen Van
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282732/
https://ncbi.nlm.nih.gov/pubmed/22363665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031535
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