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DNA binding of CPF1 is required for optimal centromere function but not for maintaining methionine prototrophy in yeast.

The centromere and promoter factor 1 (CPF1) binds specifically in vitro and in vivo to an octanucleotide (RTCACRTG). This sequence is found in the centromere DNA element I (CDEI) of yeast centromeres and upstream from a number of transcription units including MET25, GAL2 and TRP1. Inactivation of th...

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Udgivet i:Nucleic Acids Res
Principais autores: Mellor, J, Rathjen, J, Jiang, W, Barnes, C A, Dowell, S J
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1991
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC328258/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2057354/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.11.2961
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