Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral infection

The inflammatory response to lung infections must be tightly regulated, enabling pathogen elimination while maintaining crucial gas exchange. Using recently described “depletion of regulatory T cell” (DEREG) mice, we found that selective depletion of regulatory T cells (Tregs) during acute respirato...

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Hlavní autoři: Loebbermann, J, Thornton, H, Durant, L, Sparwasser, T, Webster, K E, Sprent, J, Culley, F J, Johansson, C, Openshaw, P J
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282434/
https://ncbi.nlm.nih.gov/pubmed/22236998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2011.62
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