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Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral infection

The inflammatory response to lung infections must be tightly regulated, enabling pathogen elimination while maintaining crucial gas exchange. Using recently described “depletion of regulatory T cell” (DEREG) mice, we found that selective depletion of regulatory T cells (Tregs) during acute respirato...

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Detalhes bibliográficos
Main Authors: Loebbermann, J, Thornton, H, Durant, L, Sparwasser, T, Webster, K E, Sprent, J, Culley, F J, Johansson, C, Openshaw, P J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282434/
https://ncbi.nlm.nih.gov/pubmed/22236998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2011.62
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