Directed antigen targeting in vivo identifies a role for CD103(+) dendritic cells in both tolerogenic and immunogenic T-cell responses

The αE integrin chain CD103 identifies a subset of migratory dendritic cells (DCs) in the gut, lung, and skin. To gain further understanding of the function of CD103(+) DCs in regulating adaptive immunity in vivo, we coupled ovalbumin (OVA) to the CD103 antibody M290 (M290.OVA). Intraperitoneal inje...

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Autors principals: Semmrich, M, Plantinga, M, Svensson-Frej, M, Uronen-Hansson, H, Gustafsson, T, Mowat, A M, Yrlid, U, Lambrecht, B N, Agace, W W
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282433/
https://ncbi.nlm.nih.gov/pubmed/22166938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2011.61
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