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Loss of PTEN is associated with elevated EGFR and HER2 expression and worse prognosis in salivary gland cancer
BACKGROUND: Activity of the tumour-suppressor gene PTEN is reduced in different types of cancer and implicates non-responsiveness to targeted therapy. This study evaluates the gene and protein status of PTEN in salivary gland carcinomas. METHODS: A total of 287 carcinomas of the major and minor sali...
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| Huvudupphovsmän: | , , , , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Nature Publishing Group
2012
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3282188/ https://ncbi.nlm.nih.gov/pubmed/22240798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.605 |
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