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“Replicated” genome wide association for dependence on illegal substances: genomic regions identified by overlapping clusters of nominally positive SNPs

Declaring “replication” from results of genome wide association (GWA) studies is straightforward when major gene effects provide genome-wide significance for association of the same allele of the same SNP in each of multiple independent samples. However, such unambiguous replication may be unlikely...

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Detalhes bibliográficos
Main Authors: Drgon, Tomas, Johnson, Catherine, Nino, Michelle, Drgonova, Jana, Walther, Donna, Uhl, George R
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282182/
https://ncbi.nlm.nih.gov/pubmed/21302341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.31143
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