Genetic variation in CACNA1C affects brain circuitries related to mental illness

CONTEXT: The CACNA1C gene (alpha 1C subunit of the L-type voltage-gated calcium channel) has been identified as a risk gene for both bipolar disorder and schizophrenia but the mechanism of association has not been explored. OBJECTIVE: To identify the neural system mechanism that explains the genetic...

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Detalhes bibliográficos
Main Authors: Bigos, Kristin L., Mattay, Venkata S., Callicott, Joseph H., Straub, Richard E., Vakkalanka, Radhakrishna, Kolachana, Bhaskar, Hyde, Thomas M., Lipska, Barbara K., Kleinman, Joel E., Weinberger, Daniel R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282053/
https://ncbi.nlm.nih.gov/pubmed/20819988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archgenpsychiatry.2010.96
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