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Differences in MEF2 and NFAT Transcriptional Pathways According to Human Heart Failure Aetiology

BACKGROUND: Ca(2+) handling machinery modulates the activation of cardiac transcription pathways involved in heart failure (HF). The present study investigated the effect of HF aetiology on Ca(+2) handling proteins and NFAT1, MEF2C and GATA4 (transcription factors) in the same cardiac tissue. METHOD...

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Autori principali: Cortés, Raquel, Rivera, Miguel, Roselló-Lletí, Esther, Martínez-Dolz, Luis, Almenar, Luis, Azorín, Inmaculada, Lago, Francisca, González-Juanatey, José Ramón, Portolés, Manuel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281902/
https://ncbi.nlm.nih.gov/pubmed/22363514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030915
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