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Single Point Mutation in Bin/Amphiphysin/Rvs (BAR) Sequence of Endophilin Impairs Dimerization, Membrane Shaping, and Src Homology 3 Domain-mediated Partnership

Bin/Amphiphysin/Rvs (BAR) domain-containing proteins are essential players in the dynamics of intracellular compartments. The BAR domain is an evolutionarily conserved dimeric module characterized by a crescent-shaped structure whose intrinsic curvature, flexibility, and ability to assemble into hig...

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Detalhes bibliográficos
Principais autores: Gortat, Anna, San-Roman, Mabel Jouve, Vannier, Christian, Schmidt, Anne A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281743/
https://ncbi.nlm.nih.gov/pubmed/22167186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.325837
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