Characterization of Central Carbon Metabolism of Streptococcus pneumoniae by Isotopologue Profiling

The metabolism of Streptococcus pneumoniae was studied by isotopologue profiling after bacterial cultivation in chemically defined medium supplemented with [U-(13)C(6)]- or [1,2-(13)C(2)]glucose. GC/MS analysis of protein-derived amino acids showed lack of (13)C label in amino acids that were also e...

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Main Authors: Härtel, Tobias, Eylert, Eva, Schulz, Christian, Petruschka, Lothar, Gierok, Philipp, Grubmüller, Stephanie, Lalk, Michael, Eisenreich, Wolfgang, Hammerschmidt, Sven
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281726/
https://ncbi.nlm.nih.gov/pubmed/22167202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.304311
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