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Transcriptional and Posttranscriptional Regulation of HIV-1 Gene Expression

Control of HIV-1 gene expression depends on two viral regulatory proteins, Tat and Rev. Tat stimulates transcription elongation by directing the cellular transcriptional elongation factor P-TEFb to nascent RNA polymerases. Rev is required for the transport from the nucleus to the cytoplasm of the un...

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Autori principali: Karn, Jonathan, Stoltzfus, C. Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281586/
https://ncbi.nlm.nih.gov/pubmed/22355797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a006916
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