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Targeting the Anti-Apoptotic Protein c-FLIP for Cancer Therapy

Cellular FLICE (FADD-like IL-1beta-converting enzyme)-inhibitory protein (c-FLIP) is a major resistance factor and critical anti-apoptotic regulator that inhibits tumor necrosis factor-alpha (TNF-alpha), Fas-L, and TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis as well as chemothera...

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Detalhes bibliográficos
Main Authors: Safa, Ahmad R., Pollok, Karen E.
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281420/
https://ncbi.nlm.nih.gov/pubmed/22348197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers3021639
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