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Evolution of Resistance to Aurora Kinase B Inhibitors in Leukaemia Cells

Aurora kinase inhibitors are new mitosis-targeting drugs currently in clinical trials for the treatment of haematological and solid malignancies. However, knowledge of the molecular factors that influence sensitivity and resistance remains limited. Herein, we developed and characterised an in vitro...

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Hlavní autoři: Failes, Timothy W., Mitic, Gorjana, Abdel-Halim, Heba, Po'uha, Sela T., Liu, Marjorie, Hibbs, David E., Kavallaris, Maria
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281142/
https://ncbi.nlm.nih.gov/pubmed/22359551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030734
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