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Real-time PCR-based assay to quantify the relative amount of human and mouse tissue present in tumor xenografts
BACKGROUND: Xenograft samples used to test anti-cancer drug efficacies and toxicities in vivo contain an unknown mix of mouse and human cells. Evaluation of drug activity can be confounded by samples containing large amounts of contaminating mouse tissue. We have developed a real-time quantitative p...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3281124/ https://ncbi.nlm.nih.gov/pubmed/22176647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-11-124 |
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