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Control of Tissue Growth and Cell Transformation by the Salvador/Warts/Hippo Pathway

The Salvador-Warts-Hippo (SWH) pathway is an important regulator of tissue growth that is frequently subverted in human cancer. The key oncoprotein of the SWH pathway is the transcriptional co-activator, Yes-associated protein (YAP). YAP promotes tissue growth and transformation of cultured cells by...

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Detalles Bibliográficos
Main Authors: Zhang, Xiaomeng, Grusche, Felix A., Harvey, Kieran F.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281119/
https://ncbi.nlm.nih.gov/pubmed/22359650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031994
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