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Deciphering the Preference and Predicting the Viability of Circular Permutations in Proteins

Circular permutation (CP) refers to situations in which the termini of a protein are relocated to other positions in the structure. CP occurs naturally and has been artificially created to study protein function, stability and folding. Recently CP is increasingly applied to engineer enzyme structure...

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Autors principals: Lo, Wei-Cheng, Dai, Tian, Liu, Yen-Yi, Wang, Li-Fen, Hwang, Jenn-Kang, Lyu, Ping-Chiang
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281007/
https://ncbi.nlm.nih.gov/pubmed/22359629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031791
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